Synaptotagmin V (SYT5) Rabbit Polyclonal Antibody

CAT#: TA322891

Anti-SYT5 Rabbit Polyclonal Antibody


USD 345.00

4 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: Human cerebrum tissue, PC3 cell lysates
IHC: 50-200
Positive control: Human esophagus cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 46-200 amino acids of human synaptotagmin V
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 43 kDa
Gene Name synaptotagmin 5
Background Synaptotagmins; such as SYT5; are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C regulatory (C2) domains; which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion; allowing fusion in the presence of calcium; and as calcium receptors or sensor molecules. May be involved in Ca2+-dependent exocytosis of secretory vesicles through Ca2+ and phospholipid binding to the C2 domain or may serve as Ca2+ sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca2+-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface.
Synonyms synaptotagmin 5; synaptotagmin V
Reference Data
Protein Families Secreted Protein, Transmembrane

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.