SNAP25 Rabbit Polyclonal Antibody

CAT#: TA322908

Anti-SNAP25 Rabbit Polyclonal Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane: Hela cells Primary antibody: TA322908 (SNAP25 Antibody) at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 3 seconds

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA322908 (SNAP25 Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA322908 (SNAP25 Antibody) at dilution 1/25, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA322908 (SNAP25 Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA322908 (SNAP25 Antibody) at dilution 1/25, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Hela cells
  IHC: 25-100
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Full length fusion protein
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 23 kDa
• Gene Name: synaptosome associated protein 25kDa
• Database Link:
  NP_003072
  Entrez Gene 20614 MouseEntrez Gene 25012 RatEntrez Gene 6616 Human
  UniProt ID P60880
• Background: Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices; one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane; the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore; this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.?
• Synonyms: bA416N4.2; dJ1068F16.2; RIC-4; RIC4; SEC9; SNAP; SNAP-25

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: SNARE interactions in vesicular transport