SLC10A1 Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 15-50 Positive control: Human lung cancer Predicted cell location: Cytoplasm |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region derived from 2-15 amino acids of Human solute carrier family 10 (sodium/bile acid cotransporter family), member 1 |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | solute carrier family 10 member 1 |
Database Link | |
Background | The protein encoded by this gene belongs to the sodium/bile acid cotransporter family; which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen; bile duct and kidney; and the liver-specific sodium/bile acid cotransporter; represented by this protein; that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism; hence this protein is important for cholesterol homeostasis. |
Synonyms | NTCP |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
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