SLC10A1 Rabbit Polyclonal Antibody

CAT#: TA322912

Anti-SLC10A1 Rabbit Polyclonal Antibody


USD 345.00

4 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 15-50
Positive control: Human lung cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 2-15 amino acids of Human solute carrier family 10 (sodium/bile acid cotransporter family), member 1
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name solute carrier family 10 member 1
Background The protein encoded by this gene belongs to the sodium/bile acid cotransporter family; which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen; bile duct and kidney; and the liver-specific sodium/bile acid cotransporter; represented by this protein; that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism; hence this protein is important for cholesterol homeostasis.
Synonyms NTCP
Reference Data
Protein Families Druggable Genome, Transmembrane

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.