SLC1A4 Rabbit Polyclonal Antibody

CAT#: TA322914

Anti-SLC1A4 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human liver cancer tissue
  IHC: 25-100
  Positive control: Human cervical cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 520-532 amino acids of Human solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 56 kDa
• Gene Name: solute carrier family 1 member 4
• Database Link:
  NP_003029
  Entrez Gene 55963 MouseEntrez Gene 305540 RatEntrez Gene 6509 Human
  UniProt ID P43007
• Background: Neutral amino acid transporter A?is a?protein?that in humans is encoded by the?SLC1A4?gene. In melanocytic cells SLC1A4 gene expression may be regulated by?MITF. ASCT1 does not transport glutamate or aspartate but alanine; serine; cysteine; and threonine instead. ASCT1 transporter functions primarily as an amino acid exchanger. Transport is associated with a chloride channel activity that is thermodynamically uncoupled from amino acid transport.
• Synonyms: ASCT1; SATT; SPATCCM

Reference Data

• Protein Families: Druggable Genome, Transmembrane