Parvalbumin (PVALB) Rabbit Polyclonal Antibody

CAT#: TA322948

Anti-PVALB Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human fetal brain tissue
  IHC: 25-100
  Positive control: Human brain
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 2-110 amino acids of human parvalbumin
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 12 kDa
• Gene Name: parvalbumin
• Database Link:
  NP_002845
  Entrez Gene 19293 MouseEntrez Gene 25269 RatEntrez Gene 5816 Human
  UniProt ID P20472
• Background: Parvalbumin?is a?calcium-binding?albumin?protein with low molecular weight (typically 9-11 kDa). It has three?EF hand?motifs and is structurally related to?calmodulin?and?troponin C. Parvalbumin is localised in fast-contracting muscles; where its levels are highest; and in the brain and some endocrine tissues. Parvalbumin is a small; stable protein containing EF-hand type calcium binding sites. It is involved in calcium signaling. Typically; this protein is broken into three domains; domains AB; CD and EF; each individually containing a helix-loop-helix motif.
• Synonyms: D22S749