PSMB9 Rabbit Polyclonal Antibody

CAT#: TA322957

Anti-PSMB9 Rabbit Polyclonal Antibody

Product Images

Predicted band size: 23 kDa. Positive control: Raji, HepG2, THP-1 and Du145 cell, mouse liver tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lane 1: Raji cell lysate Lane 2: HepG2 cell lysate Lane 3: THP-1 cell lysate Lane 4: Du145 cell lysate Lane 5: Mouse liver tissue lysate Lysates: 40 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Full length fusion protein
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 23 kDa
• Gene Name: proteasome subunit beta 9
• Database Link:
  NP_002791
  Entrez Gene 16912 MouseEntrez Gene 24967 RatEntrez Gene 5698 Human
  UniProt ID P28065
• Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit.
• Synonyms: beta1i; LMP2; PSMB6i; RING12

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Proteasome