Cytokeratin 4 (KRT4) Rabbit Polyclonal Antibody

CAT#: TA323032

Anti-KRT4 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: Hela cell
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 151-461 amino acids of human keratin 4
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 57 kDa
• Gene Name: keratin 4
• Database Link:
  NP_002263
  Entrez Gene 16682 MouseEntrez Gene 315323 RatEntrez Gene 3851 Human
  UniProt ID P19013
• Background: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus; characterized by oral; esophageal; and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
• Synonyms: CK-4; CK4; CYK4; K4; WSN1