IRF1 Rabbit Polyclonal Antibody

CAT#: TA323047

Anti-IRF1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: NIH/3T3 and Jurkat cells
  IHC: 50-200
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide peptide corresponding to a region derived from 220-233 amino acids of human interferon regulatory factor 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 37 kDa
• Gene Name: interferon regulatory factor 1
• Database Link:
  NP_002189
  Entrez Gene 16362 MouseEntrez Gene 24508 RatEntrez Gene 3659 Human
  UniProt ID P10914
• Background: IRF1 encodes interferon regulatory factor 1; a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription; and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha; beta; and gamma. Further; IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.?
• Synonyms: IRF-1; MAR

Reference Data

• Protein Families: Druggable Genome, Transcription Factors