Tenascin C (TNC) Rabbit Polyclonal Antibody

CAT#: TA323051

Anti-TNC Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human esophagus cancer
  Predicted cell location: Secreted, ExtraCellular matrix
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 2187-2201 amino acids of human tenascin C
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: tenascin C
• Database Link:
  NP_002151
  Entrez Gene 21923 MouseEntrez Gene 116640 RatEntrez Gene 3371 Human
  UniProt ID P24821
• Background: This gene encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. This protein is homohexameric with disulfide-linked subunits; and contains multiple EGF-like and fibronectin type-III domains. It is implicated in guidance of migrating neurons as well as axons during development; synaptic plasticity; and neuronal regeneration.
• Synonyms: 150-225; DFNA56; GMEM; GP; HXB; JI; TN; TN-C

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
• Protein Pathways: ECM-receptor interaction, Focal adhesion