CFHL1 (CFHR1) Rabbit Polyclonal Antibody
Other products for "CFHR1"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | ELISA: 1:2000-5000, WB: 1:500-2000, IHC: 1:50-200 |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein corresponding to a region derived from 22-330 amino acids of human complement factor H-related 1 |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 38 kDa |
Gene Name | complement factor H related 1 |
Database Link | |
Background | This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen; which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface; controlling complement; and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.? |
Synonyms | CFHL; CFHL1; CFHL1P; CFHR1P; FHR1; H36-1; H36-2; HFL1; HFL2 |
Reference Data | |
Protein Families | Secreted Protein |
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