GLP1 (GCG) Rabbit Polyclonal Antibody

CAT#: TA323066

Anti-GCG Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 10-50
  Positive control: Human breast cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 1-15 amino acids of Human glucagon
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: glucagon
• Database Link:
  NP_002045
  Entrez Gene 14526 MouseEntrez Gene 24952 RatEntrez Gene 2641 Human
  UniProt ID P01275
• Background: The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these; glucagon; is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally; the fourth peptide is similar to glicentin; an active enteroglucagon.
• Synonyms: GLP1; GLP2; GRPP

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein