EGR1 Rabbit Polyclonal Antibody

CAT#: TA323079

Anti-EGR1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: RAW264.7 and NIH/3T3 cells
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 87-337 amino acids of human early growth response 1early growth response 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 58 kDa
• Gene Name: early growth response 1
• Database Link:
  NP_001955
  Entrez Gene 13653 MouseEntrez Gene 24330 RatEntrez Gene 1958 Human
  UniProt ID P18146
• Background: EGR-1 (Early growth response protein 1) also known as Zif268 (zinc finger protein 225) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site).
• Synonyms: AT225; G0S30; KROX-24; NGFI-A; TIS8; ZIF-268; ZNF225

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Prion diseases