Collagen II (COL2A1) Rabbit Polyclonal Antibody

CAT#: TA323106

Anti-COL2A1 Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications ELISA, IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: Rat skeletal muscle tissue lysate
IHC: 50-200
Positive control: Human liver cancer
Predicted cell location: Secreted
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Full length fusion protein
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 30 kDa
Gene Name collagen type II alpha 1 chain
Background This gene encodes the alpha-1 chain of type II collagen; a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis; chondrodysplasia; early onset familial osteoarthritis; SED congenita; Langer-Saldino achondrogenesis; Kniest dysplasia; Stickler syndrome type I; and spondyloepimetaphyseal dysplasia Strudwick type. In addition; defects in processing chondrocalcin; a calcium binding protein that is the C-propeptide of this collagen molecule; are also associated with chondrodysplasia. There are two transcripts identified for this gene.
Synonyms ANFH; AOM; COL11A3; SEDC; STL1
Reference Data
Protein Pathways ECM-receptor interaction, Focal adhesion

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