RUNX1 Rabbit Polyclonal Antibody

CAT#: TA323125

Anti-CBFA2 Rabbit Polyclonal Antibody

Product Images

Predicted band size: 26kDa. Positive control: Human urinary bladder tissue lysate. Recommended dilution: 1/500-2000

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:500-5000, WB: 1:500-2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 201-215 amino acids of Human Core-binding factor subunit alpha-2
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 26 kDa
• Gene Name: runt related transcription factor 1
• Database Link:
  NP_001745
  Entrez Gene 12394 MouseEntrez Gene 50662 RatEntrez Gene 861 Human
  UniProt ID Q01196
• Background: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene
• Synonyms: AML1; AML1-EVI-1; AMLCR1; CBFA2; EVI-1; PEBP2aB

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors
• Protein Pathways: Acute myeloid leukemia, Chronic myeloid leukemia, Pathways in cancer