Fibrillarin (FBL) Rabbit Polyclonal Antibody

CAT#: TA323170

Anti-FBL Rabbit Polyclonal Antibody

Product Images

Predicted band size: 34 kDa. Positive control: 293, Hela cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 10%SDS-PAGE Lane 1, 2: 293 and Hela cells lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide sequence around aa.297~301( L-T-L-E-P) derived from Human Fibrillarin
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 34 kDa
• Gene Name: fibrillarin
• Database Link:
  NP_001427
  Entrez Gene 14113 MouseEntrez Gene 292747 RatEntrez Gene 2091 Human
  UniProt ID P22087
• Background: Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
• Synonyms: FIB; FLRN; RNU3IP1

Reference Data

• Protein Families: Stem cell - Pluripotency