BID Rabbit Polyclonal Antibody

CAT#: TA323207

Anti-BID Rabbit Polyclonal Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 30 μg Lane 1-3: Human fetal brain tissue HT29 cells HepG2 cells Primary antibody: TA323207 (BID Antibody) at dilution 1/220 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds

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  Immunohistochemistry of paraffin-embedded Human renal cancer tissue using TA323207 (BID Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human renal cancer tissue using TA323207 (BID Antibody) at dilution 1/25, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-2000
  WB positive control: Human fetal brain tissue, HT-29 and HepG2 cells
  IHC: 25-100
  Positive control: Human renal cancer
  Predicted cell location: Cytoplasm, Cell membrane
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Full length fusion protein
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 22 kDa
• Gene Name: BH3 interacting domain death agonist
• Database Link:
  NP_001187
  Entrez Gene 12122 MouseEntrez Gene 64625 RatEntrez Gene 637 Human
  UniProt ID P55957
• Background: This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein; and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found; but the full-length nature of some variants has not been defined.
• Synonyms: FP497

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Natural killer cell mediated cytotoxicity, p53 signaling pathway, Pathways in cancer, Viral myocarditis