Adrenomedullin (ADM) Rabbit Polyclonal Antibody

CAT#: TA323219

Anti-ADM Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human breast cancer
  Predicted cell location: Secreted
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 129-141 amino acids of human adrenomedullin
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: adrenomedullin
• Database Link:
  NP_001115
  Entrez Gene 11535 MouseEntrez Gene 25026 RatEntrez Gene 133 Human
  UniProt ID P35318
• Background: Adrenomedullin; a hypotensive peptide found in human pheochromocytoma; consists of 52 amino acids; has 1 intramolecular disulfide bond; and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor; called preproadrenomedullin; is 185 amino acids long. By RNA-blot analysis; human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns; with the 5-prime flanking region containing TATA; CAAT; and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element.
• Synonyms: AM; PAMP

Reference Data

• Protein Families: Druggable Genome, Secreted Protein