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Adrenomedullin (ADM) Rabbit Polyclonal Antibody
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Other products for "ADM"
Specifications
| Product Data | |
| Applications | IHC |
| Recommended Dilution | IHC: 25-100 Positive control: Human lymphoma Predicted cell location: Secreted |
| Reactivities | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 129-141 amino acids of human adrenomedullin |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Gene Name | adrenomedullin |
| Database Link | |
| Background | Adrenomedullin; a hypotensive peptide found in human pheochromocytoma; consists of 52 amino acids; has 1 intramolecular disulfide bond; and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor; called preproadrenomedullin; is 185 amino acids long. By RNA-blot analysis; human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns; with the 5-prime flanking region containing TATA; CAAT; and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element. |
| Synonyms | AM; PAMP |
| Reference Data | |
| Protein Families | Druggable Genome, Secreted Protein |
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