Heparanase 1 (HPSE) Rabbit Polyclonal Antibody

CAT#: TA323271

Anti-HPSE Rabbit Polyclonal Antibody

Product Images

Predicted band size: 61 kDa. Positive control: 231 cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 60 ug Primary antibody: 1/100 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 5 minutes)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:2000-5000, WB: 1:500-2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a C terminal 250 amino acids of human heparanase
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 61 kDa
• Gene Name: heparanase
• Database Link:
  NP_001092010
  Entrez Gene 15442 MouseEntrez Gene 64537 RatEntrez Gene 10855 Human
  UniProt ID Q9Y251
• Background: Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix. The protein encoded by this gene is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. In addition; this cleavage can release bioactive molecules from the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.
• Synonyms: HPA; HPA1; HPR1; HPSE1; HSE1

Reference Data

• Protein Families: Secreted Protein
• Protein Pathways: Glycosaminoglycan degradation, Metabolic pathways