AADAC Rabbit Polyclonal Antibody

CAT#: TA323312

Anti-AADAC Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

Other products for "AADAC"

Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: Human fetal liver and liver cancer tissue
IHC: 25-100
Positive control: Human colon cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to C terminal 250 amino acids of human arylacetamide deacetylase
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 46 kDa
Gene Name arylacetamide deacetylase
Background Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase; which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens. Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide; which is an antiandrogen drug used for the treatment of prostate cancer that occasionally causes severe hepatotoxicity. Displays cellular triglyceride lipase activity in liver. Increases intracellular fatty acids derived from hydrolysis of newly formed triglyceride stores.
Synonyms CES5A1; DAC
Reference Data
Protein Families Druggable Genome, Transmembrane

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