NFkB p100 / p52 (NFKB2) Rabbit Polyclonal Antibody

CAT#: TA323313

Anti-NFKB2 Rabbit Polyclonal Antibody

Product Images

Predicted band size: 97 kDa. Positive control: HT-29 and SKOV3 cell lysate. Recommended dilution: 1/1000-5000

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: U251, MCF-7, HT-29 cell lysates
  IHC: 50-200
  Positive control: Human gastric cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide peptide corresponding to a region derived from 865-880 amino acids of human nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 97 kDa
• Gene Name: nuclear factor kappa B subunit 2
• Database Link:
  NP_001070962
  Entrez Gene 18034 MouseEntrez Gene 309452 RatEntrez Gene 4791 Human
  UniProt ID Q00653
• Background: This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor; depending on its dimer partner. Alternate splicing results in both coding and non-coding variants.?
• Synonyms: CVID10; H2TF1; LYT-10; LYT10; NF-kB2; p52; p100

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: MAPK signaling pathway, Pathways in cancer