NFkB p100 / p52 (NFKB2) Rabbit Polyclonal Antibody

CAT#: TA323314

Anti-NFKB2 Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA323314 (NFKB2 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA323314 (NFKB2 Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human cervical cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide peptide corresponding to a region derived from 865-880 amino acids of human nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: nuclear factor kappa B subunit 2
• Database Link:
  NP_002493
  Entrez Gene 18034 MouseEntrez Gene 309452 RatEntrez Gene 4791 Human
  UniProt ID Q00653
• Background: This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor; depending on its dimer partner. Alternate splicing results in both coding and non-coding variants.?
• Synonyms: CVID10; H2TF1; LYT-10; LYT10; NF-kB2; p52; p100

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: MAPK signaling pathway, Pathways in cancer