PAR6 (PARD6A) Rabbit Polyclonal Antibody
Other products for "PARD6A"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 500-2000 WB positive control: Human fetal muscle tissue |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide peptide corresponding to a region derived from 334-346 amino acids of human par-6 partitioning defective 6 homolog alpha (C. elegans) |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 37 kDa |
Gene Name | par-6 family cell polarity regulator alpha |
Database Link | |
Background | This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants; encoding different isoforms; have been characterized. |
Synonyms | PAR-6A; PAR6; PAR6alpha; PAR6C; TAX40; TIP-40 |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Endocytosis, Tight junction |
Documents
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