Prostate Specific Antigen (KLK3) Rabbit Polyclonal Antibody

CAT#: TA323386

Anti-KLK3 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human cervical cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to N terminal 258 amino acids of Human Kallikrein-3
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: kallikrein related peptidase 3
• Database Link:
  NP_001639
  Entrez Gene 354 Human
  UniProt ID P07288
• Background: KLK3 is a member of the kallikrein-related peptidase family secreted by the epithelial cells of the prostate gland and lead to the liquefaction of the seminal coagulum. It is thought to function normally in the liquefaction of seminal coagulum; presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein; called PSA in the clinical setting; is useful in the diagnosis and monitoring of prostatic carcinoma.
• Synonyms: APS; hK3; KLK2A1; PSA

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein
• Protein Pathways: Pathways in cancer, Prostate cancer