TRAF5 Rabbit Polyclonal Antibody

CAT#: TA323403

Anti-TRAF5 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Jurkat cells
  IHC: 25-100
  Positive control: Human lung cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 403-557 amino acids of human TNF receptor-associated factor 5
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 64 kDa
• Gene Name: TNF receptor associated factor 5
• Database Link:
  NP_001029082
  Entrez Gene 22033 MouseEntrez Gene 684173 RatEntrez Gene 7188 Human
  UniProt ID O00463
• Background: The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain; a RING-type zinc finger; and two TRAF-type zinc fingers. TRAF proteins are associated with; and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Alternate transcriptional splice variants have been characterized.
• Synonyms: MGC:39780; RNF84

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Pathways in cancer, Small cell lung cancer