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APLP1 Rabbit Polyclonal Antibody
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Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommended Dilution | WB: 500-2000 WB positive control: Human fetal brain tissue IHC: 10-50 Positive control: Human breast cancer Predicted cell location: Cytoplasm |
| Reactivities | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 56-342 of Human Amyloid beta (A4) precursor-like protein 1 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 72 kDa |
| Gene Name | amyloid beta precursor like protein 1 |
| Database Link | |
| Background | This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. |
| Synonyms | APLP |
| Reference Data | |
| Protein Families | Druggable Genome, Transmembrane |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.