AGPAT2 Rabbit Polyclonal Antibody

CAT#: TA323423

Anti-AGPAT2 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human fetal liver cancer tissue
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 244-278 amino acids of human 1-acylglycerol-3-phosphate O-acyltransferase 2
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 27 kDa
• Gene Name: 1-acylglycerol-3-phosphate O-acyltransferase 2
• Database Link:
  NP_001012745
  Entrez Gene 67512 MouseEntrez Gene 311821 RatEntrez Gene 10555 Human
  UniProt ID O15120
• Background: This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid; the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL); or Berardinelli-Seip syndrome; a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants; encoding different isoforms; have been characterized.
• Synonyms: 1-AGPAT2; BSCL; BSCL1; LPAAB; LPAAT-beta

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Ether lipid metabolism, Glycerolipid metabolism, Glycerophospholipid metabolism, Metabolic pathways