Midkine (MDK) Rabbit Polyclonal Antibody

CAT#: TA323466

Anti-MDK Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human colon cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 21-143 amino acids of human midkine (neurite growth-promoting factor 2)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: midkine (neurite growth-promoting factor 2)
• Database Link:
  NP_002382
  Entrez Gene 17242 MouseEntrez Gene 81517 RatEntrez Gene 4192 Human
  UniProt ID P21741
• Background: This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth; migration; and angiogenesis; in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
• Synonyms: ARAP; MK; NEGF2

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane