Sumo 1 (SUMO1) Rabbit Polyclonal Antibody

CAT#: TA323482

Anti-SUMO1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human ovarian cancer
  Predicted cell location: Nucleus, Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to N terminal 15 amino acids of human SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: small ubiquitin-like modifier 1
• Database Link:
  NP_003343
  Entrez Gene 22218 MouseEntrez Gene 301442 RatEntrez Gene 7341 Human
  UniProt ID P63165
• Background: This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However; unlike ubiquitin which targets proteins for degradation; this protein is involved in a variety of cellular processes; such as nuclear transport; transcriptional regulation; apoptosis; and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized.
• Synonyms: DAP1; GMP1; OFC10; PIC1; SENP2; SMT3; SMT3C; SMT3H3; UBL1

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency, Transcription Factors