RBMS3 Rabbit Polyclonal Antibody

CAT#: TA323498

Anti-RBMS3 Rabbit Polyclonal Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane: Human liver cancer tissue Primary antibody: TA323498 (RBMS3 Antibody) at dilution 1/1000 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 20 seconds

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA323498 (RBMS3 Antibody) at dilution 1/70 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA323498 (RBMS3 Antibody) at dilution 1/70, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA323498 (RBMS3 Antibody) at dilution 1/70 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA323498 (RBMS3 Antibody) at dilution 1/70, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: Human liver cancer tissue
  IHC: 50-100
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 425-437 amino acids of Human RNA binding motif, single stranded interacting protein 3
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 48 kDa
• Gene Name: RNA binding motif single stranded interacting protein 3
• Database Link:
  NP_001003793
  Entrez Gene 207181 MouseEntrez Gene 680726 RatEntrez Gene 27303 Human
  UniProt ID Q6XE24
• Background: This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs; RNP1 and RNP2; originally described in RNA binding proteins; and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication; gene transcription; cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism; rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: FLJ36544