GAS 6 (GAS6) Rabbit Polyclonal Antibody

CAT#: TA323562

Anti-GAS6 Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 10-50
Positive control: Human ovarian cancer
Predicted cell location: Cytoplasm, Nucleus
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 690-705 amino acids of Human growth arrest-specific 6
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name growth arrest specific 6
Background This gene product is a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation; and may play a role in thrombosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Ligand for tyrosine-protein kinase receptors AXL; TYRO3 and MER whose signaling is implicated in cell growth and survival; cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis; optimal cytokine signaling during human natural killer cell development; hepatic regeneration; gonadotropin-releasing hormone neuron survival and migration; platelet activation; or regulation of thrombotic responses.
Synonyms AXLLG; AXSF
Reference Data
Protein Families Druggable Genome, Secreted Protein

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