Glutathione Reductase (GSR) Rabbit Polyclonal Antibody

CAT#: TA323577

Anti-GSR Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 1000-5000
WB positive control: Jurkat, Hela and A549 cells
IHC: 50-200
Positive control: Human cervical cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 274-475 amino acids of human glutathione reductase
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 56 kDa
Gene Name glutathione reductase
Background This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense; and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH; which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Synonyms HEL-75
Reference Data
Protein Families Druggable Genome
Protein Pathways Glutathione metabolism

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.