Sodium Potassium ATPase (ATP1A1) Rabbit Polyclonal Antibody

CAT#: TA323580

Anti-ATP1A1 Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 25-100
Positive control: Human brain
Predicted cell location: Cytoplasm
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 897-911 amino acids of human ATPase, Na+/K+ transporting, alpha 1 polypeptide
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name ATPase Na+/K+ transporting subunit alpha 1
Background The protein encoded by this gene belongs to the family of P-type cation transport ATPases; and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation; for sodium-coupled transport of a variety of organic and inorganic molecules; and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits; a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms MGC3285; MGC51750
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cardiac muscle contraction

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