Elastin (ELN) Rabbit Polyclonal Antibody

CAT#: TA323639

Anti-ELN Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human hepatocellsular carcinoma tissue
  IHC: 50-200
  Positive control: Human ovarian cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 358-658 amino acids of human elastin
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 69 kDa
• Gene Name: elastin
• Database Link:
  NP_000492
  Entrez Gene 13717 MouseEntrez Gene 25043 RatEntrez Gene 2006 Human
  UniProt ID P15502
• Background: This gene encodes a protein that is one of the two components of elastic fibers. The encoded protein is rich in hydrophobic amino acids such as glycine and proline; which form mobile hydrophobic regions bounded by crosslinks between lysine residues. Deletions and mutations in this gene are associated with supravalvular aortic stenosis (SVAS) and autosomal dominant cutis laxa. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: SVAS; WBS; WS

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane