Aquaporin 2 (AQP2) Rabbit Polyclonal Antibody

CAT#: TA323648

Anti-AQP2 Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human renal cancer tissue using TA323648 (AQP2 Antibody) at dilution 1/50. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human renal cancer
  Predicted cell location: Cytoplasm, Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 255-271 amino acids of Human Aquaporin-2
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: aquaporin 2
• Database Link:
  NP_000477
  Entrez Gene 11827 MouseEntrez Gene 25386 RatEntrez Gene 359 Human
  UniProt ID P41181
• Background: The basic job of aquaporin 2 is to reabsorb water from the urine while its being removed from the blood by the kidney. Aquaporin 2 is in kidney epithelial cells and usually lies dormant in intracellular vesicle membranes; but when it is needed vasopressin binds to the cell surface vasopressin receptor; activating a signaling pathway that causes the aquaporin 2 containing vesicles to fuse with the plasma membrane so the aquaporin 2 can be used by the cell.
• Synonyms: AQP-CD; WCH-CD

Reference Data

• Protein Families: Druggable Genome, Transmembrane