Thrombopoietin (THPO) Rabbit Polyclonal Antibody

CAT#: TA323653

Anti-THPO Rabbit Polyclonal Antibody

Product Images

Predicted band size: 38 kDa. Positive control: 293 cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 22-349 amino acids of human Thrombopoietin
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 38 kDa
• Gene Name: thrombopoietin
• Database Link:
  NP_000451
  Entrez Gene 21832 MouseEntrez Gene 81811 RatEntrez Gene 7066 Human
  UniProt ID P40225
• Background: Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternate splicing results in multiple transcript variants of this gene.
• Synonyms: MGDF; MKCSF; ML; MPLLG; THCYT1; TPO

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Hematopoietic cell lineage