Fibrillin 1 (FBN1) Rabbit Polyclonal Antibody

CAT#: TA323729

Anti-FBN1 Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA323729 (FBN1 Antibody) at dilution 1/47 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA323729 (FBN1 Antibody) at dilution 1/47, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 2837-2853 amino acids of Human fibrillin 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: fibrillin 1
• Database Link:
  NP_000129
  Entrez Gene 14118 MouseEntrez Gene 83727 RatEntrez Gene 2200 Human
  UniProt ID P35555
• Background: This gene encodes a member of the fibrillin family. The encoded protein is a large; extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome; isolated ectopia lentis; autosomal dominant Weill-Marchesani syndrome; MASS syndrome; and Shprintzen-Goldberg craniosynostosis syndrome.
• Synonyms: ACMICD; ECTOL1; FBN; GPHYSD2; MASS; MFS1; OCTD; SGS; SSKS; WMS; WMS2

Reference Data

• Protein Families: Druggable Genome