ADA Rabbit Polyclonal Antibody

CAT#: TA323765

Anti-ADA rabbit polyclonal antibody


USD 345.00

In Stock*

Size
    • 100 ul

Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 200-1000
WB positive control: Raji cells
IHC: 25-100
Positive control: Human lung cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to C terminal 250 amino acids of human adenosine deaminase
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 41 kDa
Gene Name adenosine deaminase
Background This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.
Synonyms adenosine aminohydrolase; adenosine deaminase
Reference Data
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Primary immunodeficiency, Purine metabolism

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