FLIP (CFLAR) Rabbit Polyclonal Antibody

CAT#: TA323814

Anti-CFLAR Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human fetal kidney tissue
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide peptide corresponding to a region derived from 201-218 amino acids of human CASP8 and FADD-like apoptosis regulator
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 25 kDa
• Gene Name: CASP8 and FADD like apoptosis regulator
• Database Link:
  NP_001120656
  Entrez Gene 12633 MouseEntrez Gene 117279 RatEntrez Gene 8837 Human
  UniProt ID O15519
• Background: The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However; the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene; and partial evidence for several more variants exists.?
• Synonyms: c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; CASH; CASP8AP1; Casper; CLARP; FLAME; FLAME-1; FLAME1; FLIP

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Apoptosis