SLC9A3R2 Rabbit Polyclonal Antibody

CAT#: TA323831

Anti-SLC9A3R2 Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human renal cancer tissue using TA323831 (SLC9A3R2 Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human renal cancer tissue using TA323831 (SLC9A3R2 Antibody) at dilution 1/40, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA323831 (SLC9A3R2 Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA323831 (SLC9A3R2 Antibody) at dilution 1/40, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human renal cancer
  Predicted cell location: Cytoplasm, Endomembrane system, Peripheral membrane protein
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 275-289amino acids of human solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: SLC9A3 regulator 2
• Database Link:
  NP_004776
  Entrez Gene 65962 MouseEntrez Gene 116501 RatEntrez Gene 9351 Human
  UniProt ID Q15599
• Background: This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3; and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Synonyms: E3KARP; NHE3RF2; NHERF-2; NHERF2; OCTS2; SIP-1; SIP1; TKA-1

Reference Data

• Protein Families: Druggable Genome