alpha smooth muscle Actin (ACTA2) Rabbit Polyclonal Antibody

CAT#: TA323891

Anti-ACTA2 Rabbit Polyclonal Antibody

Product Images

Predicted band size: 42 kDa. Positive control: Jurkat and NIH/3T3 cell lysate. Recommended dilution: 1/ 2000-5000. (Gel: 10%SDS-PAGE Lane 1: Jurkat cell lysate Lane 2: NIH/3T3 cell lysate Lysates: 30 ug per lane Primary antibody: 1/2000 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:2000-10000, WB: 1:2000-5000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide (KLH-coupled) derived from human ACTA2
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 42 kDa
• Gene Name: actin, alpha 2, smooth muscle, aorta
• Database Link:
  NP_001135417
  Entrez Gene 11475 MouseEntrez Gene 59 Human
  UniProt ID P62736
• Background: The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Synonyms: AAT6; ACTSA; MYMY5

Reference Data

• Protein Pathways: Vascular smooth muscle contraction