NADPH oxidase 4 (NOX4) Rabbit Polyclonal Antibody

CAT#: TA323912

Anti-NOX4 Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA323912 (NOX4 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA323912 (NOX4 Antibody) at dilution 1/20, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human gasrtic cancer
  Predicted cell location: cytoplasm, Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 210-424 amino acids of human NADPH oxidase 4
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: NADPH oxidase 4
• Database Link:
  NP_058627
  Entrez Gene 50490 MouseEntrez Gene 85431 RatEntrez Gene 50507 Human
  UniProt ID Q9NPH5
• Background: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction; cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
• Synonyms: KOX; KOX-1; RENOX

Reference Data

• Protein Families: Druggable Genome, Transmembrane