Nrf2 (NFE2L2) Rabbit Polyclonal Antibody

CAT#: TA323944

Anti-NFE2L2 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: NIH/3T3 and A172 cell lysates
  IHC: 50-200
  Positive control: Human tonsil
  Predicted cell location: Cytoplasm and Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to C terminal 300 amino acids of human nuclear factor (erythroid-derived 2)-like 2
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 68 kDa
• Gene Name: nuclear factor, erythroid 2 like 2
• Database Link:
  NP_001138884
  Entrez Gene 18024 MouseEntrez Gene 83619 RatEntrez Gene 4780 Human
  UniProt ID Q16236
• Background: This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.?
• Synonyms: NRF2

Reference Data

• Protein Families: Transcription Factors