DISC1 Rabbit Polyclonal Antibody

CAT#: TA323971

Anti-DISC1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 737-750 amino acids of Human disrupted in schizophrenia 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 60 kDa
• Gene Name: disrupted in schizophrenia 1
• Database Link:
  NP_001158017
  Entrez Gene 244667 MouseEntrez Gene 307940 RatEntrez Gene 27185 Human
  UniProt ID Q9NRI5
• Background: This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus; cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants; encoding different isoforms; have been characterized.
• Synonyms: C1orf136; SCZD9