Calpain 2 (CAPN2) Rabbit Polyclonal Antibody

CAT#: TA323974

Anti-CAPN2 Rabbit Polyclonal Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 30 μg Lane 1-2: 293T cells Mouse skin tissue Primary antibody: TA323974 (CAPN2 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 50 seconds

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 200-1000
  WB positive control: 293T cells and Mouse skin tissue
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 530-700 amino acids of Human Calpain-2 catalytic subunit
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 80 kDa
• Gene Name: calpain 2
• Database Link:
  NP_001139540
  Entrez Gene 12334 MouseEntrez Gene 29154 RatEntrez Gene 824 Human
  UniProt ID P17655
• Background: The calpains; calcium-activated neutral proteases; are nonlysosomal; intracellular cysteine proteases. The mammalian calpains include ubiquitous; stomach-specific; and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large; catalytic subunits associated with a common small; regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme; calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene.
• Synonyms: CANP2; CANPL2; CANPml; mCANP

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Alzheimer's disease, Apoptosis, Focal adhesion