BAG1 Rabbit Polyclonal Antibody

CAT#: TA324019

Anti-BAG1 rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 50 μg Lane 1-3: Hela cells K562 cells Raji cells Primary antibody: TA324019 (BAG1 Antibody) at dilution 1/750 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 seconds

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA324019 (BAG1 Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA324019 (BAG1 Antibody) at dilution 1/40, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Hela, K562 and Raji cells
  IHC: 50-200
  Positive control: Human thyroid cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 116-345 amino acids of human BCL2-associated athanogene
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 39 kDa
• Gene Name: BCL2 associated athanogene 1
• Database Link:
  NP_001165886
  Entrez Gene 12017 MouseEntrez Gene 297994 RatEntrez Gene 573 Human
  UniProt ID Q99933
• Background: The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
• Synonyms: HAP; RAP46

Reference Data

• Protein Families: Druggable Genome