PPP2R2A Rabbit Polyclonal Antibody

CAT#: TA324040

Anti-PPP2R2A Rabbit Polyclonal Antibody

Product Images

Predicted band size: 52 kDa. Positive control: Rat brain tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 50-280 amino acids of human protein phosphatase 2, regulatory subunit B, alpha
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 52 kDa
• Gene Name: protein phosphatase 2 regulatory subunit Balpha
• Database Link:
  NP_001171062
  Entrez Gene 71978 MouseEntrez Gene 117104 RatEntrez Gene 5520 Human
  UniProt ID P63151
• Background: Protein phosphatase 2A subunit B isoform R2-a (PPP2R2A) is the component of regulatory subunit B of serine/threonine protein phosphatase 2A (PP2A). PPP2R2A belongs to the R2/B55/PR55 family of regulatory subunit B. Evidence suggests that subunit PPP2R2A enhances TGF-β, Activin, and Nodal signaling pathways and may play an important role in cell cycle regulation. PPP2R2A/PP2A, B55-a/PR55-a isoform interacts with the type I TGF-β receptors via unique WD-40 repeats that contribute to the anti-proliferative function of TGF-β receptors.
• Synonyms: B55A; B55ALPHA; PR52A; PR55A

Reference Data

• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Tight junction