ACOX1 Rabbit Polyclonal Antibody

CAT#: TA324047

Anti-ACOX1 rabbit polyclonal antibody

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Mouse stomach, liver and kidney tissue
  IHC: 15-50
  Positive control: Human cervical cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to C terminal 250 amino acids of human acyl-CoA oxidase 1, palmitoyl
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 74 kDa
• Gene Name: acyl-CoA oxidase 1, palmitoyl
• Database Link:
  NP_001171968
  Entrez Gene 11430 MouseEntrez Gene 50681 RatEntrez Gene 51 Human
  UniProt ID Q15067
• Background: The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Synonyms: ACOX; PALMCOX; SCOX

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: alpha-Linolenic acid metabolism, Biosynthesis of unsaturated fatty acids, Fatty acid metabolism, Metabolic pathways, PPAR signaling pathway