PRMT7 Rabbit Polyclonal Antibody

CAT#: TA324051

Anti-PRMT7 Rabbit Polyclonal Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications ELISA, WB
Recommended Dilution WB: 500-2000
WB positive control: Human liver cancer tissue
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 526-692 amino acids of human protein arginine methyltransferase 7
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 78 kDa
Gene Name protein arginine methyltransferase 7
Background Protein arginine methyltransferase 7?is a?protein?that in humans is encoded by the?PRMT7?gene.?Arginine?methylation?is an apparently irreversible protein modification catalyzed by arginine methyltransferases; such as PMT7; using?S-adenosylmethionine?(AdoMet) as the methyl donor. Arginine methylation is implicated in?signal transduction; RNA transport; and?RNA splicing. May be involved in etoposide-induced cytotoxicity; a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT).
Synonyms FLJ10640; KIAA1933
Reference Data
Protein Families Druggable Genome

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