PIWIL1 Rabbit Polyclonal Antibody

CAT#: TA324094

Anti-PIWIL1 Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA324094 (PIWIL1 Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA324094 (PIWIL1 Antibody) at dilution 1/25, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA324094 (PIWIL1 Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA324094 (PIWIL1 Antibody) at dilution 1/25, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human colon cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 555-847 amino acids of human piwi-like RNA-mediated gene silencing 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: piwi like RNA-mediated gene silencing 1
• Database Link:
  NP_004755
  Entrez Gene 57749 MouseEntrez Gene 363912 RatEntrez Gene 9271 Human
  UniProt ID Q96J94
• Background: This gene encodes a member of the PIWI subfamily of Argonaute proteins; evolutionarily conserved proteins containing both PAZ and Piwi motifs that play important roles in stem cell self-renewal; RNA silencing; and translational regulation in diverse organisms. The encoded protein may play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: CT80.1; HIWI; MIWI; PIWI

Reference Data

• Protein Pathways: Dorso-ventral axis formation